1. Alpha-blockers: Combining Fildena with alpha-blockers can also cause a significant drop in blood pressure, leading to symptoms such as dizziness, fainting, and lightheadedness. 2. Other ED medications: Concurrent use of Fildena with other medications used to treat ED, such as Cialis or Levitra, should be avoided due to the increased risk of adverse effects and complications. 3. Hypersensitivity: Individuals with a known hypersensitivity or allergy to sildenafil or any of the inactive ingredients in Fildena should not use this medication.